Table 1: Different rodent models with the signs of metabolic syndrome.

Rodent model Age (weeks)Signs of metabolic syndrome shown by rodents References
ObesityHypertensionDyslipidaemiaCardiovascular dysfunctionImpaired glucose toleranceFatty liverKidney dysfunction

ob/ob mice4×××××U[3339]
12×××U
24××U

db/db mice6×××××U[4144]
12-13××U
20×U

ZDF rat12–15×××[4753]
20××
31–47×

OLETF rats8××××××[5861]
14×××××
20××××
24×××
34××
40×
60–66

Goto-Kakizaki rats4××××××[6467]
8××××
20×××
60××

This table represents the signs of metabolic syndrome at different ages. The symbols and × indicate the presence and absence of these signs of metabolic syndrome at that age, respectively, whereas U indicates unavailability of the data. The table indicates that age is an important parameter since some of the signs are developed in very young rodents whereas others take much longer to develop.