Experimentally Approaching the ICU: Monitoring Outcome-Based Responses in the Two-Hit Mouse Model of Posttraumatic Sepsis

Figure 3

Retrospective comparison of red blood cell, platelet count, and hemoglobin concentration in dying (DIE) versus surviving (SUR) animals prior to CLP. 3-month-old female mice were subjected to trauma/hemorrhage prior to CLP. Displayed values were compared between DIE and SUR at −48 h (DIE at least 𝑛=17, SUR at least 𝑛=18), −24 h (DIE at least 𝑛=28, SUR 𝑛=32), 0 h before-CLP (DIE at least 𝑛=28, SUR 𝑛=32 for all parameters) and between time points. Dots represent outlayers. ^§𝑃<.05 between time points, and *𝑃<.05 between DIE and SUR.

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