Improving Antigenicity of the Recombinant Hepatitis C Virus Core Protein via Random Mutagenesis
Figure 3
Saturation curves for urea-denatured (a) and refolded (b) forms of HCV core antigens. Antigenicity of unfolded (a) and refolded (b) forms of HCV core antigens were examined by ELISA using the microplate that had been coated with different amounts of Wt (•), M1a (∘), M1b (▾), M2 (▽), M3a (■), and M3b(□).
