Table 1: KL (affinity) and Amax (maximum binding capacity) of HCV core antigens.

Wild typeM1aM1bM2M3aM3b
Core proteinUaRbR/UURR/UURR/UURR/UURR/UURR/U

KL ( M−1) 0.9 0.9 0.9 0.8 1.2 1.3
Amax (10−2) 1.2 1.2 1.2 1.3 1.2 1.2

Rsqr0.960.920.970.940.970.960.970.950.980.940.930.91

a, bUn-folded and refolded protein, respectively.