Transversal Stiffness and Beta-Actin and Alpha-Actinin-4 Content of the M. Soleus Fibers in the Conditions of a 3-Day Reloading after 14-Day Gravitational Unloading

Table 1

Transversal stiffness (pN/nm) of isolated permeabilized Sol muscle fibers in liquid in relaxed, calcium-activated (𝑝𝐶𝑎=4.2), and rigor states under 14-day gravitational unloading and 3-day reloading.

State group	Relaxed	Activated (pCa=4.2)	Rigor
Transversal stiffness of sarcolemma between the M-band and Z-disk projections 𝑘⟂𝑠
Control	2.94±0.14	3.09±0.17	3.72±0.15^%/#
14-HS	1.11±0.06 *	1.28±0.09 *	1.42±0.11^*/%
14-HS + 3-R	2.92±0.10^$	2.82±0.19^$	3.13±0.12^*/$
Transversal stiffness of sarcolemma at the M-band projection 𝑘⟂𝑀𝑙𝑠
Control	2.15±0.14	2.73±0.13^%	3.25±0.19^%/#
14-HS	0.99±0.11 *	1.36±0.12^*/%	1.81±0.14^*/%/#
14-HS + 3-R	2.11±0.12^$	2.76±0.22^$/%	3.36±0.21^$/%/#
Transversal stiffness of sarcolemma at the Z-disk projection 𝑘⟂𝑍𝑑𝑠
Control	3.25±0.18	3.58±0.16^%	4.15±0.17^%/#
14-HS	1.32±0.12 *	1.83±0.13^*/%	2.01±0.12^*/%/#
14-HS + 3-R	3.01±0.13^$	3.33±0.11^$/%	3.96±0.17^$/%/#

* 𝑃<0.05 as compared to the analogous state of the group “Control,” ^$𝑃<0.05 as compared to the analogous state of the group “14-HS,” ^%𝑃<0.05 as compared to the relaxed state at the same group, ^#𝑃<0.05 as compared to the activated state at the same group.