Histological findings at postinjection 7 weeks. Tumor was observed under the retina near optic nerve and in the vitreous (hematoxylin-eosin, ×40, (a)). Occasional tumor seeds in the vitreous exhibited central necrosis (×100, (b)). Cuffs of viable tumor cells surrounded the blood vessels with regions of necrosis beginning 70–80 μm from nutrient vessels (×100, (c); ×400, (d)).