Roles of the WHHL Rabbit in Translational Research on Hypercholesterolemia and Cardiovascular Diseases

Figure 2

Development of atherosclerotic lesions in WHHLMI rabbits with age. The solid line denotes the degree of coronary atherosclerosis shown as coronary cross-sectional narrowing; lesion areas/area surrounded by the internal elastic lamina ×100 (%). The dotted line denotes the degree of aortic atherosclerosis; sum of the surface areas of the lesion/total surface area of the aortic lumen ×100 (%). Modified from Shiomi and Ito [8].