419343.fig.002a
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419343.fig.002b
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419343.fig.002c
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419343.fig.002d
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Figure 2: UA inhibited proliferation and induced apoptosis in hepatocellular carcinoma cell H22 mouse xenograft. (a) Xenografts treated with PS or UA were imaged by PET-CT. (b) Cell cycle of tumor cells from xenografts treated with PS or UA was examined. Cell cycle distribution was showed in the table (* ). (c) Apoptosis of tumor cells from xenografts induced by UA was detected by Annexin-V staining and flow cytometry. Quantified data showed in the table below (* ). (d) Western blot showed expression of Caspase-3 and Caspase-8 in tumor cells from xenografts treated with PS or UA.