Ursolic Acid Inhibits Proliferation and Induces Apoptosis of Cancer Cells In Vitro and In Vivo
Figure 2
UA inhibited proliferation and induced apoptosis in hepatocellular carcinoma cell H22 mouse xenograft. (a) Xenografts treated with PS or UA were imaged by PET-CT. (b) Cell cycle of tumor cells from xenografts treated with PS or UA was examined. Cell cycle distribution was showed in the table (*). (c) Apoptosis of tumor cells from xenografts induced by UA was detected by Annexin-V staining and flow cytometry. Quantified data showed in the table below (*). (d) Western blot showed expression of Caspase-3 and Caspase-8 in tumor cells from xenografts treated with PS or UA.
