IgG Responses to Tissue-Associated Antigens as Biomarkers of Immunological Treatment Efficacy

Table 1

Biomarker co-occurrence among models. Feature comparison analysis describing which biomarkers have in population specific ML-BBNs. An IgG response change to Chromosome 1 gene contig CHANGE1, for example, has associations in all three population-specific ML-BBNs. Conversely, an IgG response change to Adducin 1 CHANGE only has an association in the ADT population ML-BBN.

	ADT	PAPV	PSAV	Total
Chromosome 1 gene contig CHANGE1	Yes	Yes	Yes	3
Prolactin-induced protein CHANGE	Yes	Yes	Yes	3
Acetyl-coenzyme A acyltransferase 1 CHANGE	No	Yes	Yes	2
BAC RP11-321G3 CHANGE	Yes	No	Yes	2
Cutaneous T cell CHANGE	Yes	No	Yes	2
neuronal PAS domain protein 2 CHANGE	No	Yes	Yes	2
o-fucosyltansferase CHANGE	Yes	No	Yes	2
Page 1 CHANGE	Yes	No	Yes	2
Recombination signal CHANGE	Yes	No	Yes	2
Adducin 1 CHANGE	Yes	No	No	1
caldesmon 1 (CALD1) CHANGE	No	Yes	No	1
carcimona-associated antigen 64 CHANGE	Yes	No	No	1
Chromosome 1 gene contig CHANGE	Yes	No	No	1
Chromosome 16 gene contig CHANGE	Yes	No	No	1
chromosome 17 CHANGE	Yes	No	No	1
Chromosome 20 gene CHANGE	No	Yes	No	1
Chromosome 4 gene contig CHANGE	No	Yes	No	1
FLJ10710 cDNA CHANGE	Yes	No	No	1
fms-related tyrosine kinase 3 ligand CHANGE	No	No	Yes	1
Helicase with SNF2 domain CHANGE	No	No	Yes	1
Lage 1 CHANGE	No	Yes	No	1
Mage A3 CHANGE	Yes	No	No	1
Ny-ESO1 CHANGE	Yes	No	No	1
PAP associated domain CHANGE	Yes	No	No	1
PAP ELISPOT 12 months	No	Yes	No	1
Plexin B2 CHANGE	No	Yes	No	1
polypeptide E (POLR2E) CHANGE	No	Yes	No	1
Prostate specific antigen (PSA) CHANGE	Yes	No	No	1
PSA ELISPOT 3m	No	No	Yes	1
Ribosomal protein S27a CHANGE	Yes	No	No	1
RP11-3J10 on chromosome 13 CHANGE	No	No	Yes	1
RP11-738B7 DNA on chromosome 7 CHANGE	Yes	No	No	1
RP11-746L20 DNA on chromosome 8 CHANGE	Yes	No	No	1
SPA17 CHANGE	No	Yes	No	1