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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 474632, 15 pages
MicroRNA Gene Dosage Alterations and Drug Response in Lung Cancer
1British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, Canada V5Z 1L3
2Research Institute, Nationwide Children’s Hospital, Columbus, OH 43205-2664, USA
Received 1 November 2010; Accepted 27 January 2011
Academic Editor: E. Felip
Copyright © 2011 Katey S. S. Enfield et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Supplemental Table 1 - List of 18 drugs analyzed in this study.
Supplemental Table 2 - List of lung cancer cell lines with either SNP 6.0 copy number, miRNA expression, or IC50 response.
Supplemental Table 3 - Summary of copy number alteration comparisons for all miRNAs across all drugs.
Supplemental Table 4 - miRNAs significantly differentially expressed across 18 drugs.
Supplemental Table 5 - mRNA targets found by TargetScan and TargetSpy for the four identified miRNAs.