Localization of Magic-F1 Transgene, Involved in Muscular Hypertrophy, during Early Myogenesis

Figure 5

Expression of Pax3 and Magic-F1 at 15.5 dpc. Sagittal section of 15.5 dpc mouse hybridized with digoxigenin-labeled antisense Pax3 riboprobes (a); specific Pax3 transcripts are localized in cartilage primordium of tail vertebral body, cutaneous muscles (arrow) of thorax and trunk regions and in mid-cervical region of spinal cord (double arrow) as shown in (b); expression was also localized in cartilage primordium (arrowhead) of dorsal part of shaft region (c); (d) sagittal section of 15.5 dpc mouse hybridized with Magic-F1 cRNA probes and signal is observed in cartilage primordium of anterior arch of cervical vertebra (arrowheads) and right lobe of thymus gland (arrow); specific Magic-F1 transcripts are also localized in cutaneous muscles (arrow) of thorax and trunk regions (e); (f) higher magnification cartilage primordium of dorsal part of shaft region of ribs.