510827.fig.001a
(a)
510827.fig.001b
(b)
510827.fig.001c
(c)
510827.fig.001d
(d)
Figure 1: Cystic changes develop with age in the pars distalis of Nhe2-/- mice. H&E stained sections of Nhe2-/- pituitaries were examined at the following ages: (a) 5 weeks, (b) 8 weeks, and (c) 10 weeks. Note the presence of dilated canaliculi (open spaces) at 8 weeks and 10 weeks. No cyst-like dilatations of the canaliculi were seen in the WT mice at 10 weeks (d) or earlier ages (not shown). Bar: 20 μm.