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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 520816, 7 pages
http://dx.doi.org/10.1155/2011/520816
Review Article

The Use of Pluripotent Stem Cell for Personalized Cell Therapies against Neurological Disorders

Division of Intractable Diseases, Center for Biomedical Science, Korea National Institute of Health, Cheongwon-gun, Chungbuk 363-700, Republic of Korea

Received 17 July 2011; Accepted 4 November 2011

Academic Editor: Ken-ichi Isobe

Copyright © 2011 Hye-Yeong Ha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Although there are a number of weaknesses for clinical use, pluripotent stem cells are valuable sources for patient-specific cell therapies against various diseases. Backed-up by a huge number of basic researches, neuronal differentiation mechanism is well established and pluripotent stem cell therapies against neurological disorders are getting closer to clinical application. However, there are increasing needs for standardization of the sourcing pluripotent stem cells by establishing stem cell registries and banking. Global harmonization will accelerate practical use of personalized therapies using pluripotent stem cells.