592343.fig.003
Figure 3: Schematic representation of computer-generated elastic and viscous moduli. (a)–(c) Random numbers generated from various (one example shown in (a)) were used to dictate the attachment times, , of a virtual crossbridge. (b) shows an example attachment and detachment sequence. (c) illustrates the , with and , used to dictate the intermittent times of detachment. (d) A sinusoidal length perturbation with amplitude 1 nm was used to simulate an externally applied length perturbation. This example is at 1 Hz. (e) An example series of successive crossbridge attachments and detachments would be subject to the length perturbation. (f) The length change that occurs during the time of attachment results in a force deflection. (g) The sum of these force deflections from 20,000 crossbridges is then fit to a sinusoidal (solid smooth line). (h) The magnitude of the component of the fitted sinusoid in phase with the length perturbation represents the elastic modulus at this frequency, the magnitude of the component out of phase represents the viscous modulus.