Distribution of Myosin Attachment Times Predicted from Viscoelastic Mechanics of Striated Muscle

Figure 4

Examples of results from computer simulations. (a, b) The elastic and viscous moduli are plotted against frequency for three 𝑝 and 𝛽 pairs. Nonlinear least-squares fitting of (15) to the data produced a good fit shown as the line for each pair of 𝑝 and 𝛽. (c) The parameters estimated from fitting (15) to the simulated data provided a comparison between the PDF_𝑡att(𝑡) used to generate the data and the gamma distribution predicted from the fits. In this case, the predicted gamma distributions are nearly indistinguishable from the original PDF_𝑡att(𝑡). (d) The survival function, 𝑆_𝜏(𝑡), was also predicted from the parameter estimates and again very closely resembles the original 𝑆_𝜏(𝑡).