597145.fig.004a
(a)
597145.fig.004b
(b)
Figure 4: Box plot of serum (a) miR-29a and (b) miR-21 level across stage. Expression levels of the miRNAs were normalized to RUN6B. The box represents the interquartile range, and the line across the box indicated the median value. Statistically significant differences were determined by Mann-Whitney test.