Presenilin-2 Mutation Causes Early Amyloid Accumulation and Memory Impairment in a Transgenic Mouse Model of Alzheimer's Disease

Figure 6

Kaplan-Meier survival curves of the PS2Tg2576 mice. (a) Survival plots for male mice (wild-type 𝑛=20, PS2 𝑛=12, Tg2576 𝑛=18, PS2Tg2576 𝑛=18). (b) Survival plots for female mice (wild-type 𝑛=16, PS2 𝑛=21, Tg2576 𝑛=12, PS2Tg2576 𝑛=21). Statistical significance was assessed using the original method of the log-rank test: *𝑃<.05, PS2Tg2576 versus Tg2576 mice at the same age.

(a)

(b)