Electrophoretic Mobility of Cardiac Myosin Heavy Chain Isoforms Revisited: Application of MALDI TOF/TOF Analysis

Table 1

Ratio of cardiac MyHCα/MyHCβ isoforms from left ventricles of adult euthyroid (EU), hyperthyroid (TH), and hypothyroid (HY) Lewis rats. MyHC isoforms were separated by SDS-PAGE, silver-stained, and quantified by densitometric evaluation (Quantity One Software, BioRad). The data are expressed as a mean ± SD, *significantly different from EU and TH, 𝑃<0.05, number of animals = 5.

Thyroid status	The ratio
EU	3.84 ± 0.72
TH	4.39 ± 0.63
HY	0.09 ± 0.05*