Myosin Binding Protein-C: A Regulator of Actomyosin Interaction in Striated Muscle

Figure 2

Schematic representation of cardiac MyBP-C, illustrating its domain architecture and known binding partners. Immunoglobulin and fibronectin type III domains are shown as white and grey ovals, respectively. The M-motif is denoted as a dark black line flanked by domains C1 and C2. The cardiac specific insertion within domain C5 is shown as a grey rectangle. Ligands for cMyBP-C are indicated at their sites of interaction.