Investigation of a Potential Scintigraphic Tracer for Imaging Apoptosis: Radioiodinated Annexin V-Kunitz Protease Inhibitor Fusion Protein

Figure 2

Binding of ¹²⁵I-ANV and ¹²⁵I-ANV-6L15 to erythrocyte ghosts. (a) Time course of binding of ¹²⁵I-ANV or ¹²⁵I-ANV-6L15 to ghost erythrocytes in the presence of 2.5 mM Ca²⁺ at room temperature. (b) Binding of ¹²⁵I-ANV or ¹²⁵I-ANV-6L15 to ghost erythrocytes under various concentrations of Ca²⁺. Data are expressed as mean ± SD of three independent experiments.

(a)

(b)