Research Article

Investigation of a Potential Scintigraphic Tracer for Imaging Apoptosis: Radioiodinated Annexin V-Kunitz Protease Inhibitor Fusion Protein

Table 2

Biodistribution of 123I-ANV-6L15 fusion protein in healthy BALB/c mice ( ).

Organ%ID/organ%ID/g of tissue
2 min10 min30 min60 min120 min   180 min2 min10 min30 min60 min120 min180 min

Brain
Thyroid
Heart
Lung
Liver
Spleen
Stomach
Intestine
Kidneys
Bladder
Urine
Testis
Blood*
Muscle#
Bone+

*Estimated total blood volume: 7.0% of total body weight.
#Estimated total muscle: 40.0% of total body weight.
+Estimated total bone: 6.5% of total body weight.
%ID: percentage of injected dose.
Data expressed as mean ± SD.