Natural Killer Cells in Human Cancer: From Biological Functions to Clinical Applications
Figure 2
NK cell tumor immunity and alloimmunity after allogeneic ACT. Autologous NK cell killing is inhibited when self-class I MHC on tumor cells is recognized. In allogeneic ACT, NK cell KIR-mismatch is implicated both in GVHD and in mediating of a GVL effect.