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Journal of Biomedicine and Biotechnology
Volume 2011 (2011), Article ID 691412, 17 pages
Joint Inflammation and Early Degeneration Induced by High-Force Reaching Are Attenuated by Ibuprofen in an Animal Model of Work-Related Musculoskeletal Disorder
1Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Box 406, Boston, MA 02111, USA
2College of Health Professions, Pacific University, 190 SE 8th Avenue, Suite 230, Hillsboro, OR 97123, USA
3Department of Anatomy & Cell Biology, Temple University School of Medicine, 3500 North Broad Street, Philadelphia, PA, 19140, USA
4College of Health Professions & Social Work, Temple University, 3307 North Broad Street, Suite 300, Philadelphia, PA 19140, USA
Received 12 September 2010; Accepted 11 December 2010
Academic Editor: Oreste Gualillo
Copyright © 2011 Jeffrey B. Driban et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Bureau of Labor Statistics, “Incidence of nonfatal occupational injuries and illnesses involving days away from work1 by occupation and selected parts of body affected by injury or illness,” 2006, http://www.bls.gov/iif/oshwc/osh/case/ostb1889.pdf.
- Bureau of Labor Statistics, “Number of nonfatal occupational injuries and illnesses involving days away from work1 by occupation and selected parts of body affected by injury or illness,” 2006, http://www.bls.gov/iif/oshwc/osh/case/ostb1666.pdf.
- Health Safety Executive, HSE, “Health Safety Executive, H.,” 2006, http://www.hse.gov.uk/statistics/swi/swi0405.pdf.
- Health Safety Executive, HSE, 2007, http://www.hse.gov.uk/statistics/lfs/lfs0506.pdf.
- Risquesprofessionals, “Prévention/études et dossiers/les troubles musculo—squelettiques,” http://www.risquesprofessionnels.ameli.fr/fr/rubrique/prevention_etudes-dossiers_1.php.
- K. D. Brandt, P. Dieppe, and E. L. Radin, “Etiopathogenesis of osteoarthritis,” Rheumatic Disease Clinics of North America, vol. 34, no. 3, pp. 531–559, 2008.
- R. P. Calfee, E. L. Leventhal, J. Wilkerson, D. C. Moore, E. Akelman, and J. J. Crisco, “Simulated radioscapholunate fusion alters carpal kinematics while preserving dart-thrower's motion,” Journal of Hand Surgery, vol. 33, no. 4, pp. 503–510, 2008.
- J. A. Martin and J. A. Buckwalter, “Post-traumatic osteoarthritis: the role of stress induced chondrocyte damage,” Biorheology, vol. 43, no. 3-4, pp. 517–521, 2006.
- B. Bernard, “Musculoskeletal disorders and workplace factors,” NIOSH Report 97–141, National Institute for Occupational Safety and Health, Cincinatti, Ohio, USA, 1997.
- S. Solovieva, T. Vehmas, H. Riihimäki, K. Luoma, and P. Leino-Arjas, “Hand use and patterns of joint involvement in osteoarthritis. A comparison of female dentists and teachers,” Rheumatology, vol. 44, no. 4, pp. 521–528, 2005.
- H. Ding, S. Solovieva, T. Vehmas, E. P. Takala, and P. Leino-Arjas, “Hand osteoarthritis and pinch grip strength among middle-aged female dentists and teachers,” Scandinavian Journal of Rheumatology, vol. 39, no. 1, pp. 84–87, 2010.
- L. Kalichman and G. Hernández-Molina, “Hand osteoarthritis: an epidemiological perspective,” Seminars in Arthritis and Rheumatism, vol. 39, no. 6, pp. 465–476, 2010.
- K. L. Dominick, J. M. Jordan, J. B. Renner, and V. B. Kraus, “Relationship of radiographic and clinical variables to pinch and grip strength among individuals with osteoarthritis,” Arthritis and Rheumatism, vol. 52, no. 5, pp. 1424–1430, 2005.
- M. N. Spies-Dorgelo, D. A. W. M. van der Windt, H. E. van der Horst, A. P. A. Prins, and W. A. B. Stalman, “Hand and wrist problems in general practice—patient characteristics and factors related to symptom severity,” Rheumatology, vol. 46, no. 11, pp. 1723–1728, 2007.
- A. M. Bendele, “Animal models of osteoarthritis in an era of molecular biology,” Journal of Musculoskeletal Neuronal Interactions, vol. 2, no. 6, pp. 501–503, 2002.
- A. H. A. Abd, D. A. Hume, W. J. Halliday, and G. H. G. Davis, “Immunopathological investigations during the course of arthritis induced in rats by Streptococcus agalactiae,” Medical Microbiology and Immunology, vol. 179, no. 1, pp. 13–23, 1990.
- K. Yamamoto, T. Shishido, T. Masaoka, and A. Imakiire, “Morphological studies on the ageing and osteoarthritis of the articular cartilage in C57 black mice,” Journal of Orthopaedic Surgery, vol. 13, no. 1, pp. 8–18, 2005.
- E. N. Blaney Davidson, E. L. Vitters, P. M. van der Kraan, and W. B. van den Berg, “Expression of transforming growth factor-β (TGFβ) and the TGFβ signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation,” Annals of the Rheumatic Diseases, vol. 65, no. 11, pp. 1414–1421, 2006.
- T. Hayami, M. Pickarski, Y. Zhuo, G. A. Wesolowski, G. A. Rodan, and L. T. Duong, “Characterization of articular cartilage and subchondral bone changes in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis,” Bone, vol. 38, no. 2, pp. 234–243, 2006.
- S. S. Glasson, T. J. Blanchet, and E. A. Morris, “The surgical destabilization of the medial meniscus (DMM) model of osteoarthritis in the 129/SvEv mouse,” Osteoarthritis and Cartilage, vol. 15, no. 9, pp. 1061–1069, 2007.
- A. Kadri, T. Funck-Brentano, H. Lin et al., “Inhibition of bone resorption blunts osteoarthritis in mice with high bone remodelling,” Annals of the Rheumatic Diseases, vol. 69, no. 8, pp. 1533–1538, 2010.
- M. B. Elliott, A. E. Barr, and M. F. Barbe, “Spinal substance P and neurokinin-1 increase with high repetition reaching,” Neuroscience Letters, vol. 454, no. 1, pp. 33–37, 2009.
- M. B. Elliott, A. E. Barr, B. D. Clark, M. Amin, S. Amin, and M. F. Barbe, “High force reaching task induces widespread inflammation, increased spinal cord neurochemicals and neuropathic pain,” Neuroscience, vol. 158, no. 2, pp. 922–931, 2009.
- M. B. Elliott, A. E. Barr, B. D. Clark, C. K. Wade, and M. F. Barbe, “Performance of a repetitive task by aged rats leads to median neuropathy and spinal cord inflammation with associated sensorimotor declines,” Neuroscience, vol. 170, no. 3, pp. 929–941, 2010.
- M. B. Elliott, A. E. Barr, D. M. Kietrys, T. Al-Shatti, M. Amin, and M. F. Barbe, “Peripheral neuritis and increased spinal cord neurochemicals are induced in a model of repetitive motion injury with low force and repetition exposure,” Brain Research, vol. 1218, no. C, pp. 103–113, 2008.
- B. D. Clark, T. A. Al-Shatti, A. E. Barr, M. Amin, and M. F. Barbe, “Performance of a high-repetition, high-force task induces carpal tunnel syndrome in rats,” Journal of Orthopaedic and Sports Physical Therapy, vol. 34, no. 5, pp. 244–253, 2004.
- B. D. Clark, A. E. Barr, F. F. Safadi et al., “Median nerve trauma in a rat model of work-related musculoskeletal disorder,” Journal of Neurotrauma, vol. 20, no. 7, pp. 681–695, 2003.
- M. F. Barbe, A. E. Barr, I. Gorzelany, M. Amin, J. P. Gaughan, and F. F. Safadi, “Chronic repetitive reaching and grasping results in decreased motor performance and widespread tissue responses in a rat model of MSD,” Journal of Orthopaedic Research, vol. 21, no. 1, pp. 167–176, 2003.
- M. F. Barbe, M. B. Elliott, S. M. Abdelmagid et al., “Serum and tissue cytokines and chemokines increase with repetitive upper extremity tasks,” Journal of Orthopaedic Research, vol. 26, no. 10, pp. 1320–1326, 2008.
- A. E. Barr, F. F. Safadi, I. Gorzelany, M. Amin, S. N. Popoff, and M. F. Barbe, “Repetitive, negligible force reaching in rats induces pathological overloading of upper extremity bones,” Journal of Bone and Mineral Research, vol. 18, no. 11, pp. 2023–2032, 2003.
- S. Rani, M. F. Barbe, A. E. Barr, and J. Litivn, “Role of TNF alpha and PLF in bone remodeling in a rat model of repetitive reaching and grasping,” Journal of Cellular Physiology, vol. 225, no. 1, pp. 152–167, 2010.
- S. Rani, M. F. Barbe, A. E. Barr, and J. Litvin, “Periostin-like-factor and Periostin in an animal model of work-related musculoskeletal disorder,” Bone, vol. 44, no. 3, pp. 502–512, 2009.
- M. D. Jones, C. W. Tran, G. Li, W. P. Maksymowych, R. F. Zernicke, and M. R. Doschak, “In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat,” Arthritis and Rheumatism, vol. 62, no. 9, pp. 2726–2735, 2010.
- G. X. Qiu, S. N. Gao, G. Giacovelli, L. Rovati, and I. Setnikar, “Efficacy and safety of glucosamine sulfate versus ibuprofen in patients with knee osteoarthritis,” Arzneimittel-Forschung, vol. 48, no. 5, pp. 469–474, 1998.
- D. H. Manicourt, M. Bevilacqua, V. Righini, J. P. Famaey, and J. P. Devogelaer, “Comparative effect of nimesulide and ibuprofen on the urinary levels of collagen type II C-telopeptide degradation products and on the serum levels of hyaluronan and matrix metalloproteinases-3 and -13 in patients with flare-up of osteoarthritis,” Drugs in R and D, vol. 6, no. 5, pp. 261–271, 2005.
- E. Gineyts, J. A. Mo, A. Ko et al., “Effects of ibuprofen on molecular markers of cartilage and synovium turnover in patients with knee osteoarthritis synovium turnover in patients with osteoarthritis,” Annals of the Rheumatic Diseases, vol. 63, no. 7, pp. 857–861, 2004.
- S. G. Petersen, T. Saxne, D. Heinegard et al., “Glucosamine but not ibuprofen alters cartilage turnover in osteoarthritis patients in response to physical training,” Osteoarthritis and Cartilage, vol. 18, no. 1, pp. 34–40, 2010.
- J. M. Fedorczyk, A. E. Barr, S. Rani et al., “Exposure-dependent increases in IL-1β, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury,” Journal of Orthopaedic Research, vol. 28, no. 3, pp. 298–307, 2010.
- S. S. Adams, R. G. Bough, E. E. Cliffe et al., “Some aspects of the pharmacology, metabolism, and toxicology of ibuprofen. I. Pharmacology and metabolism,” Rheumatology and physical medicine, vol. 10, pp. 10–26, 1970.
- J. O. Coq, F. Strata, M. Russier et al., “Impact of neonatal asphyxia and hind limb immobilization on musculoskeletal tissues and S1 map organization: implications for cerebral palsy,” Experimental Neurology, vol. 210, no. 1, pp. 95–108, 2008.
- J. A. van der Sluijs, R. G. T. Geesink, A. J. van der Linden, S. K. Bulstra, R. Kuyer, and J. Drukker, “The reliability of the Mankin score for osteoarthritis,” Journal of Orthopaedic Research, vol. 10, no. 1, pp. 58–61, 1992.
- R. J. H. Custers, L. B. Creemers, A. J. Verbout, M. H. P. van Rijen, W. J. A. Dhert, and D. B. F. Saris, “Reliability, reproducibility and variability of the traditional Histologic/Histochemical Grading System vs the new OARSI Osteoarthritis Cartilage Histopathology Assessment System,” Osteoarthritis and Cartilage, vol. 15, no. 11, pp. 1241–1248, 2007.
- M. R. van der Harst, J. DeGroot, G. H. Kiers, P. A. J. Brama, C. H. A. van de Lest, and P. R. van Weeren, “Biochemical analysis of the articular cartilage and subchondral and trabecular bone of the metacarpophalangeal joint of horses with early osteoarthritis,” American Journal of Veterinary Research, vol. 66, no. 7, pp. 1238–1246, 2005.
- M. R. van der Harst, P. A. J. Brama, C. H. A. van de Lest, G. H. Kiers, J. DeGroot, and P. R. van Weeren, “An integral biochemical analysis of the main constituents of articular cartilage, subchondral and trabecular bone,” Osteoarthritis and Cartilage, vol. 12, no. 9, pp. 752–761, 2004.
- S. Rani, M. F. Barbe, A. E. Barr, and J. Litvin, “Induction of periostin-like factor and periostin in forearm muscle, tendon, and nerve in an animal model of work-related musculoskeletal disorder,” Journal of Histochemistry and Cytochemistry, vol. 57, no. 11, pp. 1061–1073, 2009.
- J. Bondeson, S. D. Wainwright, S. Lauder, N. Amos, and C. E. Hughes, “The role of synovial macrophages and macrophage-produced cytokines in driving aggrecanases, matrix metalloproteinases, and other destructive and inflammatory responses in osteoarthritis,” Arthritis Research and Therapy, vol. 8, article R187, 2006.
- J. C. Fernandes, J. Martel-Pelletier, and J. P. Pelletier, “The role of cytokines in osteoarthritis pathophysiology,” Biorheology, vol. 39, no. 1-2, pp. 237–246, 2002.
- H. Hulejová, V. Barešová, Z. Klézl, M. Polanská, M. Adam, and L. Šenolt, “Increased level of cytokines and matrix metalloproteinases in osteoarthritic subchondral bone,” Cytokine, vol. 38, no. 3, pp. 151–156, 2007.
- F. Iannone, C. De Bari, F. Dell' Accio et al., “Interleukin-10 and interleukin-10 receptor in human osteoarthritic and healthy chondrocytes,” Clinical and Experimental Rheumatology, vol. 19, no. 2, pp. 139–145, 2001.
- E. V. Tchetina, G. Squires, and A. R. Poole, “Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions,” Journal of Rheumatology, vol. 32, no. 5, pp. 876–886, 2005.
- J. Wang, P. Verdonk, D. Elewaut, E. M. Veys, and G. Verbruggen, “Homeostasis of the extracellular matrix of normal and osteoarthritic human articular cartilage chondrocytes in vitro,” Osteoarthritis and Cartilage, vol. 11, no. 11, pp. 801–809, 2003.
- C. R. Scanzello, E. Umoh, F. Pessler et al., “Local cytokine profiles in knee osteoarthritis: elevated synovial fluid interleukin-15 differentiates early from end-stage disease,” Osteoarthritis and Cartilage, vol. 17, no. 8, pp. 1040–1048, 2009.
- A. R. Amin, M. Attur, R. N. Patel et al., “Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide,” Journal of Clinical Investigation, vol. 99, no. 6, pp. 1231–1237, 1997.
- H. Seki, M. Fukuda, M. Iino, T. Takahashi, and N. Yoshioka, “Immunohistochemical localization of cyclooxygenase-1 and -2 in synovial tissues from patients with internal derangement or osteoarthritis of the temporomandibular joint,” International Journal of Oral and Maxillofacial Surgery, vol. 33, no. 7, pp. 687–692, 2004.
- M. J. Benito, D. J. Veale, O. FitzGerald, W. B. van den Berg, and B. Bresnihan, “Synovial tissue inflammation in early and late osteoarthritis,” Annals of the Rheumatic Diseases, vol. 64, no. 9, pp. 1263–1267, 2005.
- L. Ning, M. Ishijima, H. Kaneko et al., “Correlations between both the expression levels of inflammatory mediators and growth factor in medial perimeniscal synovial tissue and the severity of medial knee osteoarthritis,” International Orthopaedics. In press.
- P. Wang, X. You, Y. Yan, et al., “Cyclic mechanical stretch downregulates IL-1-induced COX-2 expression and PGE2 production in rheumatoid arthritis fibroblast-like synoviocytes,” Connective Tissue Research. In press.
- K. Hu, L. Xu, L. Cao et al., “Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen,” Arthritis and Rheumatism, vol. 54, no. 9, pp. 2891–2900, 2006.
- C. M. Thomas, C. J. Fuller, C. E. Whittles, and M. Sharif, “Chondrocyte death by apoptosis is associated with cartilage matrix degradation,” Osteoarthritis and Cartilage, vol. 15, no. 1, pp. 27–34, 2007.
- P. Garnero, N. Charni, F. Juillet, T. Conrozier, and E. Vignon, “Increased urinary type II collagen helical and C telopeptide levels are independently associated with a rapidly destructive hip osteoarthritis,” Annals of the Rheumatic Diseases, vol. 65, no. 12, pp. 1639–1644, 2006.
- D. D. Frisbie, F. Al-Sobayil, R. C. Billinghurst, C. E. Kawcak, and C. W. McIlwraith, “Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses,” Osteoarthritis and Cartilage, vol. 16, no. 10, pp. 1196–1204, 2008.
- C. Ritchlin and S. A. Haas-Smith, “Expression of interleukin 10 mRNA and protein by synovial fibroblastoid cells,” Journal of Rheumatology, vol. 28, no. 4, pp. 698–705, 2001.
- P. Muller and B. Simon, “Effects of ibuprofen lysinate and acetylsalicylic acid on gastric and duodenal mucosa. Randomized single-blind placebo-controlled endoscopic study in healthy volunteers,” Arzneimittel-Forschung, vol. 44, no. 7, pp. 840–843, 1994.
- J. B. Driban, M. R. Sitler, M. F. Barbe, and E. Balasubramanian, “Is osteoarthritis a heterogeneous disease that can be stratified into subsets?” Clinical Rheumatology, vol. 29, no. 2, pp. 123–131, 2010.