Proteomic Analysis of Sera from Common Variable Immunodeficiency Patients Undergoing Replacement Intravenous Immunoglobulin Therapy
Figure 1
2-DE map of differentially expressed proteins in CVID. The figure shows the position on the master (a) and on the preparative (b) gels of the 27 deregulated spots, as revealed by the comparison of serum samples from normal and CVID patients. In (a), the spots are surrounded by a white border; matched spots within the preparative gel (b) are highlighted by a yellow circle, also indicating the picking surface for the robotic spot picker. The representative image reported in (a) shows to the Cy2-labelled proteins on the scanned master gel; protein spots in (b) were visualized by Sypro Ruby fluorescent staining.
