Research Article

Proteomic Analysis of Sera from Common Variable Immunodeficiency Patients Undergoing Replacement Intravenous Immunoglobulin Therapy

Table 2

Clinical and laboratory data of naive (N4–N9) and IVIg-treated patients (I4–I9) contributing to serum samples for western blot determinations of serum clusterin levels.

IDSex Age (years)Total protein level (g/dL)Ig level (mg/dL) ESR (mm/1st h) CRP (mg/dL) Observed complications
IgGIgAIgM

N4M336.92886.27.310<0.31R
N5F445.923512.243.5284.59R, GI
N6F305.6704.5277.54R, GI, M
N7F385.723012.143.4264.50R, GI
N8M306.269<6.2<4.54<0.31R, GI, A
N9F136.62536.28.280.75R
I4M137.44186.113.3130.35R, GI
I5M206.6100013.954120.31R, GI
I6F397.19105.815100.31R, GI
I7F196.47006.110.570.33R
I8M477.2600634.180.31R, GI, A
I9F176.74816.94.1100.31R, GI

ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; R: respiratory tract infections; GI: gastrointestinal tract infections; A: autoimmunity; M: malignancy.