Experimental Model of Zymosan-Induced Arthritis in the Rat Temporomandibular Joint: Role of Nitric Oxide and Neutrophils

Table 1

Histopathological analysis of TMJ: the effects of nitric oxide synthase (NOS) inhibitors.

	Cell influx in the synovial membrane	Synovial membrane thickness	Periarticular cell influx	Cell influx in the muscular tissue
Sham	0 (0-0)	0 (0-0)	0 (0-0)	0(0-0)
Zymosan	2.5 (1–3)*	3 (0–3)*	4 (4-4)*	3 (2–4)*
L-NAME 100 mg/kg	0.5 (0-1)^+	0 (0-0)^+	1 (0–2)^+	0 (0-0)^+
1400 W 1 mg/kg	0 (0-0)^+	0 (0-0)^+	1 (0–2)^+	0 (0-0)^+

^∗𝑃<.05 versus Sham. ⁺𝑃<.05 versus zymosan (Kruskal-Wallis, Dunn’s).