Preclinical Studies with Umbilical Cord Mesenchymal Stromal Cells in Different Animal Models for Muscular Dystrophy

Figure 1

Engraftment of male human and canine umbilical cord MSCs into muscle of female GRMD dogs. Polymerase chain reaction analysis for (a) sex-determining region Y (SRY) sequence and (b) canine-specific dystrophin sequence. Muscles samples shown are the following: (1) male cUCV MSC from L3M5; (2) male hUCT MSC; (3, 4) B144 and B312 from affected female L3F1; (5, 6) B144 and B312 from affected female L3F2; (7) female canine control DNA; (8) female human control DNA.