Magnetic Resonance Microscopy Contribution to Interpret High-Resolution Magic Angle Spinning Metabolomic Data of Human Tumor Tissue

Figure 1

The upper part shows the scheme of a rotor containing the sample and the solution and the axial MRM images of four samples. The scheme of the HRMAS rotor shows the different parts with the sample and the solution in the inner cavity. The position of the axial plane is drawn with a magenta line and the axial view of the rotor on the right (upper part) shows the axial section, which is perpendicular to the longitudinal axis of the rotor. Below, the set of MRM images shows 10 RARE axial slices and the central sagital and coronal planes for each of the samples showing the shape of tissue pieces inside the rotor for samples D, E, G, and H. The position of the 10 axial images is detailed by the 10 magenta horizontal lines in the sagital and coronal planes in each sample. Axial images are zoomed to achieve the optimal view of the sample. In these MRM RARE images the solution, the rotor, and the air outside the rotor are darker than the tissue.