Diagnosis and Prognostication of Ductal Adenocarcinomas of the Pancreas Based on Genome-Wide DNA Methylation Profiling by Bacterial Artificial Chromosome Array-Based Methylated CpG Island Amplification

Table 1

Clinicopathological parameters of patients with ductal adenocarcinomas of the pancreas.

Clinicopathological parameters	Number of patients
	Learning cohort	Validation cohort
Greatest diameter of the tumor
2.0 cm or less	2	1
More than 2.0 cm, but  no more than 4.0 cm	29	29
More than 4.0 cm	15	15
Histological classification
Well differentiated  adenocarcinoma	2	4
Moderately  differentiated  adenocarcinoma	35	30
Poorly differentiated  adenocarcinoma	6	9
Adenosquamous  carcinoma	2	1
Mucinous noncystic  carcinoma	1	1
Lymphatic vessel invasion
Negative	0	0
Positive	46	45
Venous invasion
Negative	0	0
Positive	46	45
Lymph node metastasis
Negative	13	9
Positive	33	36
Status of the surgical margin
Negative (R0^∗)	27	33
Positive (R1 or R2^∗)	19	12
Total	46	45

∗defined in [28].