Genetics, Cytogenetics, and Epigenetics of Colorectal Cancer

Table 3

The most frequent aberrations found in CRC (see the text for details).

Chromosome loss	Chromosome gain	References
18, 17p, 1p, 4, 14, 5q, 21	7, 12, X, 5, 8	Dutrillaux, 1988 [69]
18q21		Fearon et al., 1990 [70]
	20q13	Korn et al., 1999 [71]
18q	20q	De Angelis et al., 1999 [72]
18p21-pter, 15q11-q21, 17p12-13, 18q12-21	8q23-ter, 13p14-31, 20q13	Hermsen et al., 2002 [73]
4, 18p, 14q	17p, 17q, 1q11, 12p, 19	Diep et al., 2006 [74]
8p, 18q, 1p22, 4q26, 15q21	20, 8q, 8q28, 16q24.3, 20q13	Camps et al., 2006 [75]
18q	13q	Fensterer et al., 2007 [76]
18, 17p, Y, 1p3, 8p	13, 20, 7, X, 12, 6	Muleris et al., 2008 [77]
8p, 18, 18q	3, 3q, 5, 5p, 5q, 7, 8q, 20, 20q, 13, X	Knutsen et al., 2010 [78]
4, 5, 8, 10, 14, 15, 17, 18, 21, 22, Y, 18q10 [i(8) (q10)], 17q10 [i (17) (q10)]	7, 13, 20, X	Mitelman Database online