Review Article

Pathogen Recognition by the Long Pentraxin PTX3

Figure 3

Model of the PTX3-dependent opsonisation of A. fumigatus conidia. In the presence of PTX3-opsonized conidia, FcγRIIA induces inside-out CD11b/CD18 activation, recruitment to the phagocytic cup, and amplification of C3b-opsonized conidia phagocytosis.
830421.fig.003