|
| Reference | Method applied in order to induce plaque rupture and/or thrombus formation | Animal model |
|
| Reddick et al. [99] | Forceps squeezing of the aorta | Apo E-/- mice |
Gertz et al. [100]
Rekhter et al. [101] | Combination of double ballon injury and hypercholesterolemia and further angioplasty-induced plaque rupture | Rabbits |
| Eitzman et al. [102] | Photochemical reaction to previously formed atherosclerotic plaques | Apo E-/- mice |
Constantinides et al. [103]
Abela et al. [104]
Nakamura et al. [105] | Intraperitoneal injection of Russell’s viper venom* followed by i.v. injection of histamine (vasopressor), serotonin or angiotensin II | Hypercholesterolemic rabbits |
| Rekhter et al. [106] | Intracerebroventricular injection of corticotrophin-releasing factors (“stress hormone”) | Apo E-/- mice |
| Heras et al. [107] | Carotid angioplasty | Pig |
Badimon et al. [52, 108]
Lassila et al. [65] | Thrombogenic effect of shear stress and atherosclerotic vessel components on the extracorporeal perfusion system | Pig |
Badimon et al. [36]
Fuster et al. [109, 110] | Von Willebrand factor deficiency | Pigs with von Willebrand disease |
|