Effects of Theophylline on Anesthetized Malignant Hyperthermia-Susceptible Pigs

Figure 1

Central-venous pCO₂ (a), central-venous pH (b), heart rate (c), and plasma theophylline concentration (d) following cumulative intravenous administration of theophylline in malignant hyperthermia-susceptible (MHS) and normal (MHN) swine. Shown are median ± range. ^∗𝑃<0.05 MHS versus MHN; ^†𝑃<0.05 MHS versus 0 minutes; ^‡𝑃<0.05 MHN versus 0 minutes.

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