Association of Angiotensin-Converting Enzyme Intron 16 Insertion/Deletion and Angiotensin II Type 1 Receptor A1166C Gene Polymorphisms with Preeclampsia in South East of Iran

Table 2

Genotype and allele frequencies of I/D polymorphism of the ACE gene and A1166C polymorphism of the angiotensin II type-1 receptor in preeclamptic patients and controls.

	Preeclampsia; 𝑁=125	Controls; 𝑁=132	𝜒^2	𝑃 value	Odds ratio
I/D polymorphism
II, 𝑛 (%)	18 (14.5)	46 (35)
ID, 𝑛 (%)	64 (51.5)	49 (37)
DD, 𝑛 (%)	43 (34)	37 (28)
ID+DD (%)	107 (85.5)	86 (65)	14.4	0.0001	3.2 (1.7–5.9)
I (%)	0.4	0.53
D (%)	0.6	0.47
A1166C polymorphism
AA, 𝑛 (%)	109 (87)	118 (89)
AC, 𝑛 (%)	15 (12)	12 (9)
CC, 𝑛 (%)	1 (1)	2 (2)
AC+CC (%)	16 (13)	14 (11)	0.3	0.36
A (%)	0.93	0.94
C (%)	0.07	0.06