Table 2: Surgical mouse models of cutaneous disease with select references.

Mouse ModelHuman Disease RelevanceSelect References

Excisional WoundDiabetes and obesity[31, 65, 66]
Aging[67, 68]
Obesity[69]

Ischemic FlapDiabetes[35]
Aging[34]

Pressure UlcerDiabetes[37]
Decubitus ulcers[38, 39]

Mechanical LoadHypertrophic scar formation[29]

ParabiosisDiabetes, obesity[61, 62]
Ischemic wounds[59]
Scleroderma[63]
Aging[64]

Dorsal Skin Fold ChamberArteriovenous malformations[56]

XenograftingDonor graft integration[70]
Wound remodeling[71]