Mucosal Immunization Induces a Higher Level of Lasting Neutralizing Antibody Response in Mice by a Replication-Competent Smallpox Vaccine: Vaccinia Tiantan Strain
Figure 3
Anti-S neutralizing antibody responses in VTT-vaccinated mice after two i.m. MVTT-S challenges. Serum samples collected three weeks after the second MVTT-S challenge were tested in this experiment. Pooled sera, which contain an equal amount of serum of each vaccinated mouse in each group, were subjected to each experiment. The -axis represents the serum dilution factor whereas the -axis indicated the percentage of viral inhibition. The dashed horizontal line indicates IC50 values. The experiment was repeated twice with similar results obtained. As controls, no VTT represents mice, who did not receive VTT-vaccination.
