Table 2: MARV protein sequences recognized by murine H-2d CD8+ T cells. Summary of data is from [102].

MARV protein15-mer peptide sequenceMinimal peptideaAmino acid positionAdoptive transfer protectionb

GlycoproteinFLISLILIQGTKNLPILIQGTKNL11–1950
ILIQGTKNLPILEIAQGTKNLPIL14–2220
TCYNISVTDPSGKSLVTDPSGKSL97–105NT
SGKSLLLDPPTNIRDLLLDPPTNI105–1130
SPPPTPSSTAQHLVYTPSSTAQHL420–4280
GILLLLSIAVLIALSLLLSIAVLI659–667100
LSIAVLIALSCICRILSIAVLIAL661–66920
LIALSCICRIFTKYIIALSCICRI667–67540

NucleoproteinAINSGIDLGDLLEGGNSGIDLGDL43–5180
KFNTSPVAKYLRDAGNTSPVAKYL73–8120
EPHYSPLILALKTLEHYSPLILAL108–11610

VP40QHKNPNNGPLLAISGKNPNNGPLL218–22640

a9 mer peptide sequence derived from HLA binding predictions.
bPercentage of animals protected from lethal challenge with mouse-adapted Marburg virus after adoptive transfer of CD8 lymphocytes specific for the 9-mer peptide sequences.
NT: not tested.