Table 1: Known and putative TFs of the AraC/XylS family identified by a structural similarity search in the PDB.

Name (PDB code)UniProt IDDNA complex(a)Technique (Res.)(b)SpeciesBiological process

MarA (1bl0)P0ACH5YesX-ray (2.30 Å)Escherichia coliMultiple antibiotic resistance
MarA (1xs9)P0ACH5YesNMREscherichia coliMultiple antibiotic resistance
Rob (1d5y)P0ACI0YesX-ray (2.70 Å)Escherichia coliAntibiotic resistance, organic solvent tolerance and heavy-metal resistance
Ada (1u8b)P06134YesX-ray (2.10 Å)Escherichia coliRepair of and response to alkylated DNA
Ada (1zgw)P06134YesNMREscherichia coliRepair of and response to alkylated DNA
Ada (1wpk)P06134NoNMREscherichia coliRepair of and response to alkylated DNA
GadX (3mkl)B1X7X1NoX-ray (2.15 Å)Escherichia coliAcid resistance
AraC (2k9s)P0A9E0NoNMREscherichia coliTransport and catabolism of L-arabinose
TcpN or ToxT (3gbg)A5F384NoX-ray (1.90 Å)Vibrio choleraeBiosynthesis and assembly of the toxin-coregulated pilus
YesN (3lsg)Q8RGT8NoX-ray (2.05 Å)Fusobacterium nucleatumPossibly involved in plant cell wall degradation
Lin2118 protein (3oou)Q92A04NoX-ray (1.57 Å)Listeria innocuaUnknown
3oioQ7NTG7NoX-ray (1.65 Å)Chromobacterium violaceumUnknown
3mn2Q6NCA5NoX-ray (1.80 Å)Rhodopseudomonas palustrisUnknown

(a)Indicates whether the 3D protein structure was cocrystallized with DNA or not.
(b)Numbers in parenthesis refer to the resolution of crystal structures.