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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 106783, 10 pages
http://dx.doi.org/10.1155/2012/106783
Research Article

A Novel System for Rapid and Cost-Effective Production of Detection and Diagnostic Reagents of West Nile Virus in Plants

1The Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA
2College of Technology and Innovation, Arizona State University, Mesa, AZ 85212, USA

Received 1 August 2011; Accepted 2 September 2011

Academic Editor: Bradley J. Blitvich

Copyright © 2012 Junyun He et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [8 citations]

The following is the list of published articles that have cited the current article.

  • Huafang Lai, and Qiang Chen, “Bioprocessing of plant-derived virus-like particles of Norwalk virus capsid protein under current Good Manufacture Practice regulations,” Plant Cell Reports, vol. 31, no. 3, pp. 573–584, 2012. View at Publisher · View at Google Scholar
  • C.A. Martínez, A.M. Giulietti, and J. Rodríguez Talou, “Research advances in plant-made flavivirus antigens,” Biotechnology Advances, vol. 30, no. 6, pp. 1493–1505, 2012. View at Publisher · View at Google Scholar
  • Kahlin Leuzinger, Matthew Dent, Jonathan Hurtado, Jake Stahnke, Huafang Lai, Xiaohong Zhou, and Qiang Chen, “Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins,” Journal of Visualized Experiments, no. 77, pp. e50521, 2013. View at Publisher · View at Google Scholar
  • Qiang Chen, and Huafang Lai, “Plant-derived virus-like particles as vaccines,” Human vaccines & immunotherapeutics, vol. 9, no. 1, pp. 26–49, 2013. View at Publisher · View at Google Scholar
  • Huafang Lai, Junyun He, Jonathan Hurtado, Jake Stahnke, Anja Fuchs, Erin Mehlhop, Sergey Gorlatov, Andreas Loos, Michael S. Diamond, and Qiang Chen, “Structural and functional characterization of an anti-West Nile virus monoclonal antibody and its single-chain variant produced in glycoengineered plants,” Plant Biotechnology Journal, 2014. View at Publisher · View at Google Scholar
  • Junyun He, Huafang Lai, Michael Engle, Sergey Gorlatov, Clemens Gruber, Herta Steinkellner, and Michael S. Diamond, “Generation and Analysis of Novel Plant-Derived Antibody-Based Therapeutic M olecules against West Nile Virus,” Plos One, vol. 9, no. 3, 2014. View at Publisher · View at Google Scholar
  • Hyun-Soon Kim, Jae-Heung Jeon, Kyung Jin Lee, and Kisung Ko, “N-Glycosylation Modification of Plant-Derived Virus-Like Particles: An Application in Vaccines,” BioMed Research International, vol. 2014, pp. 1–8, 2014. View at Publisher · View at Google Scholar
  • Junyun He, Li Peng, Huafang Lai, Jonathan Hurtado, Jake Stahnke, and Qiang Chen, “A Plant-Produced Antigen Elicits Potent Immune Responses against West Nile Virus in Mice,” BioMed Research International, vol. 2014, pp. 1–10, 2014. View at Publisher · View at Google Scholar