Research Article

A Novel Model of Atherosclerosis in Rabbits Using Injury to Arterial Walls Induced by Ferric Chloride as Evaluated by Optical Coherence Tomography as well as Intravascular Ultrasound and Histology

Figure 4

Representative optical coherence tomography images. At 24 hours after injury, no thrombus is detected in the lumen (a). At 8 weeks after injury, atherosclerosis of the right common carotid arteries is evident (b), but not in the control (c). (d) is the same cross-section as (b) and shows evident plaque growth at 12 weeks. In the same rabbit, a typical arterial enlargement is seen (e).
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(a)
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(b)
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(c)
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(d)
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(e)