- About this Journal ·
- Abstracting and Indexing ·
- Aims and Scope ·
- Annual Issues ·
- Article Processing Charges ·
- Author Guidelines ·
- Bibliographic Information ·
- Citations to this Journal ·
- Contact Information ·
- Editorial Board ·
- Editorial Workflow ·
- Free eTOC Alerts ·
- Publication Ethics ·
- Recently Accepted Articles ·
- Reviewers Acknowledgment ·
- Submit a Manuscript ·
- Subscription Information ·
- Table of Contents
Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 131324, 6 pages
Canine Liver Transplantation Model and the Intermediate Filaments of the Cytoskeleton of the Hepatocytes
1Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, T6G 2B7, Canada
2Department of Laboratory Medicine and Pathology, Walter Mackenzie Health Sciences Centre, 5B4.09, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada
Received 10 December 2011; Accepted 27 January 2012
Academic Editor: Andrea Vecchione
Copyright © 2012 Consolato Sergi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- J. W. Kupiec-Weglinski and R. W. Busuttil, “Ischemia and reperfusion injury in liver transplantation,” Transplantation Proceedings, vol. 37, no. 4, pp. 1653–1656, 2005.
- T. E. Starzl, T. L. Marchioro, K. N. Vonkaulla, G. Hermann, R. S. Brittain, and W. R. Waddell, “Homotransplantation of the liver in humans,” Surgery, Gynecology & Obstetrics, vol. 117, pp. 659–676, 1963.
- F. Dünschede, K. Erbes, A. Kircher et al., “Reduction of ischemia reperfusion injury after liver resection and hepatic inflow occlusion by α-lipoic acid in humans,” World Journal of Gastroenterology, vol. 12, no. 42, pp. 6812–6817, 2006.
- P. A. Clavien, P. R. C. Harvey, and S. M. Strasberg, “Preservation and reperfusion injuries in liver allografts: an overview and synthesis of current studies,” Transplantation, vol. 53, no. 5, pp. 957–978, 1992.
- M. B. Omary, N. O. Ku, and D. M. Toivola, “Keratins: guardians of the liver,” Hepatology, vol. 35, no. 2, pp. 251–257, 2002.
- E. Frixione, “Recurring views on the structure and function of the cytoskeleton: a 300-year epic,” Cell Motility and the Cytoskeleton, vol. 46, no. 2, pp. 73–94, 2000.
- N. O. Ku, X. Zhou, D. M. Toivola, and M. B. Omary, “The cytoskeleton of digestive epithelia in health and disease,” American Journal of Physiology, vol. 277, no. 6, pp. G1108–G1137, 1999.
- P. Strnad, C. Stumptner, K. Zatloukal, and H. Denk, “Intermediate filament cytoskeleton of the liver in health and disease,” Histochemistry and Cell Biology, vol. 129, no. 6, pp. 735–749, 2008.
- P. Van Eyken and V. J. Desmet, “Cytokeratins and the liver,” Liver, vol. 13, no. 3, pp. 113–122, 1993.
- R. Moll, W. W. Franke, and D. L. Schiller, “The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells,” Cell, vol. 31, no. 1, pp. 11–24, 1982.
- B. W. Jackson, C. Grund, and E. Schmid, “Formation of cytoskeletal elements during mouse embryogenesis. Intermediate filaments of the cytokeratin type and desmosomes in preimplantation embryos,” Differentiation, vol. 17, no. 3, pp. 161–179, 1980.
- P. Van Eyken, R. Sciot, B. Van Damme, C. De Wolf-Peeters, and V. J. Desmet, “Keratin immunohistochemistry in normal human liver. Cytokeratin pattern of hepatocytes, bile ducts and acinar gradient,” Virchows Archiv, vol. 412, no. 1, pp. 63–72, 1987.
- P. Van Eyken, R. Sciot, F. Callea, K. Van der Steen, P. Moerman, and V. J. Desmet, “The development of the intrahepatic bile ducts in man: a keratin-immunohistochemical study,” Hepatology, vol. 8, no. 6, pp. 1586–1595, 1988.
- A. M. Bellizzi, R. D. LeGallo, J. C. Boyd, and J. C. Iezzoni, “Hepatocyte cytokeratin 7 expression in chronic allograft rejection,” American Journal of Clinical Pathology, vol. 135, no. 2, pp. 238–244, 2011.
- A. Durnez, C. Verslype, F. Nevens et al., “The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. A possible progenitor cell origin,” Histopathology, vol. 49, no. 2, pp. 138–151, 2006.
- C. Sergi, W. Gross, M. Mory, M. Schaefer, and M. M. Gebhard, “Biliary-type cytokeratin pattern in a canine isolated perfused liver transplantation model,” Journal of Surgical Research, vol. 146, no. 2, pp. 164–171, 2008.
- E. E. Montalvo-Jave, T. Escalante-Tattersfield, J. A. Ortega-Salgado, E. Piña, and D. A. Geller, “Factors in the Pathophysiology of the Liver Ischemia-Reperfusion Injury,” Journal of Surgical Research, vol. 147, no. 1, pp. 153–159, 2008.
- G. Bilbao, J. L. Contreras, D. E. Eckhoff et al., “Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene,” Annals of Surgery, vol. 230, no. 2, pp. 185–193, 1999.
- C. Fondevila, R. W. Busuttil, and J. W. Kupiec-Weglinski, “Hepatic ischemia/reperfusion injury—a fresh look,” Experimental and Molecular Pathology, vol. 74, no. 2, pp. 86–93, 2003.
- R. M. Zwacka, Y. Zhang, J. Halldorson, H. Schlossberg, L. Dudus, and J. F. Engelhardt, “CD4+ T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver,” Journal of Clinical Investigation, vol. 100, no. 2, pp. 279–289, 1997.
- H. Ajamieh, N. Merino, E. Candelario-Jalil et al., “Similar protective effect of ischaemic and ozone oxidative preconditionings in liver ischaemia/reperfusion injury,” Pharmacological Research, vol. 45, no. 4, pp. 333–339, 2002.
- V. Kohli, W. Gao, C. A. Camargo, and P. A. Clavien, “Calpain is a mediator of preservation-reperfusion injury in rat liver transplantation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 17, pp. 9354–9359, 1997.
- L. Benkoël, F. Dodero, J. Hardwigsen et al., “Effect of ischemia-reperfusion on bile canalicular F-actin microfilaments in hepatocytes of human liver allograft: image analysis by confocal laser scanning microscopy,” Digestive Diseases and Sciences, vol. 46, no. 8, pp. 1663–1667, 2001.
- M. Hesse, T. M. Magin, and K. Weber, “Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a suprisingly high number of pseudogenes related to keratin genes 8 and 18,” Journal of Cell Science, vol. 114, no. 14, pp. 2569–2575, 2001.
- A. D. Irvine and W. H. I. McLean, “Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype-genotype correlation,” British Journal of Dermatology, vol. 140, no. 5, pp. 815–828, 1999.
- N. O. Ku, R. Gish, T. L. Wright, and M. B. Omary, “Keratin 8 mutations in patients with cryptogenic liver disease,” New England Journal of Medicine, vol. 344, no. 21, pp. 1580–1587, 2001.
- G. F. Hutchins and J. L. Gollan, “Recent developments in the pathophysiology of cholestasis,” Clinics in Liver Disease, vol. 8, no. 1, pp. 1–26, 2004.
- K. Zatloukal, C. Stumptner, A. Fuchsbichler et al., “The keratin cytoskeleton in liver diseases,” Journal of Pathology, vol. 204, no. 4, pp. 367–376, 2004.
- D. Palmes and H. U. Spiegel, “Animal models of liver regeneration,” Biomaterials, vol. 25, no. 9, pp. 1601–1611, 2004.
- L. Dorn, L. F. Menezes, G. Mikuz, H. F. Otto, L. F. Onuchic, and C. Sergi, “Immunohistochemical detection of polyductin and co-localization with liver progenitor cell markers during normal and abnormal development of the intrahepatic biliary system and in adult hepatobiliary carcinomas,” Journal of Cellular and Molecular Medicine, vol. 13, no. 7, pp. 1279–1290, 2009.