Table 1: Mouse strains. Mouse strains used in the study and number of animals studied per strain.

StrainSourceJAX mice database stock #DYSF mutationN

A/WySnJSchool of Medicine University of Maryland. Breeding pairs from The Jackson Laboratory000647N/A. Control strain for A/J mice8
A/JSchool of Medicine University of Maryland. Breeding pairs from The Jackson Laboratory000646A retrotransposon insertion within intron 4, causing aberrant splicing of the gene8
C57Bl/6JThe Jackson Laboratory000664N/A. Background strain for B6.A/J8
B6.A/JSchool of Medicine University of Maryland. Breeding pairs from The Jackson Laboratory012767 B6.A-Dysfprmd/GeneJProgressive muscular dystrophy (prmd) allele from A/J introgressed into the C57BL/6J genetic background8
SWR/JThe Jackson Laboratory000689N/A. Control strain for SJL/J mice8
SJL/JThe Jackson Laboratory000686171 bp in-frame deletion in the encoded mRNA is predicted to remove 57 amino acids from dysferlin8
C57BL/10JThe Jackson Laboratory000665Background strain for B10.SJL8
B10.SJLSchool of Medicine University of Maryland. Breeding pairs from The Jackson Laboratory, and Dr. A. J. Wagers, Harvard University, Cambridge, MA.011128 B10.SJL-Dysfim/AwaJDYSF mutation (inflammatory myopathy, im) in the SJL strain introgressed into the C57BL/10ScSnHim strain and subsequently bred to C57Bl/10J8
DMDmdxSchool of Medicine University of Maryland. Breeding pairs from The Jackson Laboratory001801 C57BL/10ScSn- Dmdmdx/JN/A. Dystrophin-deficient mice. C-to-T transition at position 3185, resulting in a termination codon in place of a glutamine codon8