Table 1: The human ficolins.

M-ficolin L-ficolin H-ficolin Molecular size (subunit) 35 K 35 K 34 K Molecular size (native) 900 K 420 K 610 K Location Neutrophils, monocytes > serum liver; serum liver; bile; lung; serum Chemical specificity Acetylated sugars acetylated compounds; LPS; 1,3-β-glucans; lipoteichoic acids; elastin; steroids D-fucose > GlcNAc; polysaccharide from A.viridans Microbial specificity E. coli; S. aureus;  S. agalactiae S. aureus; S. pneumoniae; S. typhimurium; E. coli; P. aeruginosa; M. bovis; G. lamblia; T. cruzi; A. fumigatus, A. viridans; T. cruzi Complement activation Yes Yes Yes Opsonic activity ? Yes ? Collagenase sensitivity Yes Yes No