Commercial Dengue Rapid Diagnostic Tests for Point-of-Care Application: Recent Evaluations and Future Needs?

Table 1

Characteristics of dengue rapid diagnostic tests mentioned in this paper.

Manufacturer	Product name	Analytes	Storage temperature (°C)	Quoted accuracy (Sn/Sp^a)	Sample^b	1^0/2^0 c	Format^d	Sample volume (ul)	Maximum time (min)^e
Merlin	Dengue Fever IgG and IgM Combo Device	IgM/IgG	2–30°C	IgM 96/98; IgG 97/98	S/P/WB	Yes	LF	1	30
Standard Diagnostics	BIOLINE Dengue Duo NS1 antigen and IgG and IgM Combo Device	NS1 Ag; IgM/IgG	1–30°C	NS1-Ag 92.8/98.4; IgM/IgG 99.4/93.0	S/P/WB	Yes	LF	NS1-Ag 100; IgM/IgG 10	20
Biosynex	Immunoquick Dengue Fever IgG and IgM	IgM/IgG	2–30°C	IgM 97.6/98.3; IgG 95.2/96.6	S/P/WB	Yes	W	1	20
Biorad	STRIP	NS1 Ag	2–8°C	NS1-Ag 92.3/98.8	S/P	No	W	50	15
Alere	Panbio Dengue Early Rapid Kit	NS1 Ag	2–8°C	Not stated	S	No	LF	50	15
Alere	Panbio Dengue Duo Cassette	IgM/IgG	2–8°C	S^b convalescent—1^0c−85.1/91.6; 2^0−98.8/91.6; P acute—1^0−58.3/45.0; 2^0−100/45.0; WB acute—1^0−71.4/91.2; 2^0−77.4/91.2; WB convalescent—1^0−78.6/85.3; 2^0−100/85.3	S/P/WB	Yes	LF	10	15
MP Diagnostics	ASSURE	IgA	2–28°C	Not stated	S/P/WB	No	LF	25	15–20

Sn/sp^a: sensitivity/specificity.
^bS–serum; P: plasma; WB: whole blood.
^cPrimary and secondary infections: manufacturer claims RDT can differentiate
^dW: wickstyle; LF: lateral flow.
^eMaximum time in minutes to confirm a negative result.