170958.fig.002
Figure 2: Relationship between logarithm of local anesthetic concentration producing 50% of the local anesthetic-induced maximal contraction (ED50) in isolated endothelium-denuded aorta and logarithm of octanol/buffer partition coefficient (log 𝑃 ) of local anesthetics. All values are shown as mean ± SD. Each anesthetic was tested in aortic rings from six rats.