Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex
Figure 1
Immobility time of rats during the FST after intraperitoneal injection of tramadol at different doses. Tramadol administered at the dose of 10 mg/kg significantly decreased the immobility time as compared to saline (*), while tramadol administered at the doses of 2.5 and 5 mg/kg both did not affect the immobility time ().
