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Journal of Biomedicine and Biotechnology
Volume 2012 (2012), Article ID 180363, 9 pages
http://dx.doi.org/10.1155/2012/180363
Research Article

Mechanism of Growth Inhibition of Prostate Cancer Xenografts by Valproic Acid

1James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, Marburg 205A, 600 North Wolfe Street, Baltimore, MD 21287, USA
2Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
3Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Received 20 May 2012; Revised 16 July 2012; Accepted 17 July 2012

Academic Editor: Eric W. Lam

Copyright © 2012 Abhinav Sidana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [7 citations]

The following is the list of published articles that have cited the current article.

  • Xiaofei Li, Yanshuang Zhu, Huabin He, Lianqing Lou, Weiwei Ye, Yongxin Chen, and Jinghe Wang, “Synergistically killing activity of aspirin and histone deacetylase inhibitor valproic acid (VPA) on hepatocellular cancer cells,” Biochemical and Biophysical Research Communications, vol. 436, no. 2, pp. 259–264, 2013. View at Publisher · View at Google Scholar
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  • Jinhua Tang, Haidong Yan, and Shougang Zhuang, “Histone deacetylases as targets for treatment of multiple diseases,” Clinical Science, vol. 124, no. 11, pp. 651–662, 2013. View at Publisher · View at Google Scholar
  • Xi-Dong Yu, Qiang Li, Gang Xie, and Yue Teng, “Chloroquine and Valproic Acid Combined Treatment in Vitro has Enhanced Cyto toxicity in an Osteosarcoma Cell Line,” Asian Pacific Journal of Cancer Prevention, vol. 14, no. 8, pp. 4651–4654, 2013. View at Publisher · View at Google Scholar
  • Johanna L. Hannan, Omer Kutlu, Bernard L. Stopak, Xiaopu Liu, Fabio Castiglione, Petter Hedlund, Arthur L. Burnett, and Trinity J. Bivalacqua, “Valproic Acid Prevents Penile Fibrosis and Erectile Dysfunction in Cavernous Nerve-Injured Rats,” The Journal of Sexual Medicine, 2014. View at Publisher · View at Google Scholar
  • Masako Fujioka-Kobayashi, Go Ohe, Kanae Hara, Natsumi Takamaru, Daisuke Uchida, Tetsuya Tamatani, Kenji Fujisawa, and Youji Miyamoto, “Antitumour effect of valproic acid against salivary gland cancer in vitro a nd in vivo,” Oncology Reports, vol. 31, no. 3, pp. 1453–1458, 2014. View at Publisher · View at Google Scholar
  • Zheng-Hong Peng, and Jindřich Kopeček, “Synthesis and Activity of Tumor-Homing Peptide iRGD and Histone Deacetylase Inhibitor Valproic Acid Conjugate,” Bioorganic & Medicinal Chemistry Letters, 2014. View at Publisher · View at Google Scholar