Table 1: Immunohistochemistry staining scores of various markers in xenografts of control and treatment arm.

LnCaPC4-2DU145
Weighted IHC score Weighted IHC score Weighted IHC score
No Tx0.4% VPA Fold changeP valueNo Tx0.4% VPAFold changeP valueNo Tx0.4% VPAFold changeP value

H3Ac144.7175.81.220.038164.8199.21.210.032189.8212.61.120.016
p212.07.03.500.04652.691.91.750.03340.962.61.530.029
Cyclin D1120.2102.80.850.030160.0128.80.800.001149.4111.30.740.006
p270.65.34.080.03520.127.11.350.65867.291.31.360.012
CK181.32.82.220.31415.445.12.920.030113.3180.01.590.042
AR159.0132.30.830.050147.2145.4◁▷0.990.8600.00.0
Ki67130.7144.4◁▷1.110.405124.4135.0◁▷
1.080.248118.380.70.680.042
TUNEL91.9111.91.220.03987.2129.21.480.007179.4195.6◁▷1.090.145

# microvessel/mm2 # microvessel/mm2 # microvessel/mm2

MVD (CD34)57.5638.840.670.00857.0823.450.410.01031.2825.250.810.142

▲: significant increase, ∆: nonsignificant increase, ▼: significant decrease, ▽: non significant decrease, ◁▷: no change.