Research Article

Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns: Experimental Model

Table 1

Effect of topical administration of hydrogel containing 100 μg per mL isolectin Cramoll 1,4 on the hematological parameters of Wistar rats. Assays performed in triplicate for each parameter. G1 = Treatment, G2 = control. Mean ± SD ( 𝑛 = 2 ).

Parameters7th day14th day21st day28th day35th day
G1G2G1G2G1G2G1G2G1G2

Erythrogram
Erythrocytes mil/mm3 6 . 7 ± 0 . 0 1 7 . 2 ± 0 . 1 4 7 . 1 ± 0 . 1 6 7 . 5 7 ± 0 . 6 9 7 . 6 ± 0 . 6 9 7 . 5 ± 0 . 4 2 6 . 3 2 ± 0 . 5 6 8 . 1 ± 0 . 2 1 6 . 3 ± 0 . 7 1 7 . 7 ± 0 . 9 2
Hemoglobin g/dL 1 3 . 9 ± 0 . 0 1 1 3 ± 0 . 1 4 1 4 . 8 ± 0 . 5 2 1 5 . 5 9 ± 0 . 4 1 1 5 . 6 ± 0 . 4 1 1 2 . 4 ± 0 . 6 4 1 3 . 7 ± 0 . 3 8 1 2 . 8 ± 0 . 4 9 1 4 . 1 ± 0 . 3 2 1 4 . 5 ± 0 . 4 2
Hematocrit % 3 8 . 7 ± 0 . 2 2 4 1 . 1 ± 0 . 4 9 4 0 . 6 ± 0 . 5 6 4 3 . 2 2 ± 0 . 9 6 4 3 . 2 ± 0 . 9 6 4 1 ± 0 . 8 5 3 8 . 5 ± 0 . 5 5 3 9 . 8 ± 0 . 9 2 4 1 . 9 ± 0 . 8 4 4 0 . 8 ± 0 . 4 9
Platelet count
Platelets mil/mm3 8 4 4 0 0 0 ± 0 . 7 1 8 0 5 0 0 0 ± 0 . 7 1 6 5 6 0 0 0 ± 0 . 7 1 9 2 6 0 0 0 ± 0 7 1 7 8 8 0 0 0 ± 0 . 7 1 8 2 0 0 0 0 ± 0 . 7 1 8 4 4 0 0 0 ± 0 . 7 1 7 8 9 0 0 0 ± 0 . 7 1 7 4 9 0 0 0 ± 0 . 7 1 8 9 2 0 0 0 ± 0 . 7 1
WBC
Leukocytes % 7 2 0 0 ± 0 . 7 1 8 0 0 0 ± 0 . 7 1 8 1 0 0 ± 0 . 7 1 7 9 0 0 ± 0 . 7 1 1 2 0 0 0 ± 0 . 7 1 8 1 0 0 ± 0 . 7 1 9 3 0 0 ± 0 . 7 1 7 9 0 0 ± 0 . 7 1 8 0 0 0 ± 0 . 7 1 8 0 0 0 ± 0 . 7 1
Neutrophils % 1 5 . 1 ± 0 . 0 7 2 6 . 8 ± 0 . 7 8 2 6 . 4 ± 0 . 2 8 3 1 . 3 ± 0 . 5 6 8 . 7 ± 0 . 6 3 2 8 . 8 ± 0 . 4 2 1 4 . 7 ± 0 . 7 1 2 7 . 5 ± 0 . 7 1 1 6 . 1 ± 0 . 2 3 3 . 1 ± 0 . 9 9
Eosinophils % 0 ± 0 0 . 1 ± 0 . 1 4 0 . 1 ± 0 . 0 7 1 . 6 ± 0 . 2 8 0 . 1 ± 0 . 0 7 2 . 4 ± 0 . 2 8 0 . 1 ± 0 . 1 4 1 . 3 ± 0 . 1 4 0 . 1 ± 0 1 . 5 ± 0 . 0 7
Basophils % 0 . 2 ± 0 0 . 2 ± 0 . 1 4 0 . 2 ± 0 . 0 7 0 . 2 ± 0 0 . 2 ± 0 0 . 2 ± 0 . 1 4 0 . 2 ± 0 0 . 2 ± 0 0 0 . 2 ± 0 0 . 1 ± 0
typical lymphocytes % 8 1 . 4 ± 0 . 6 4 8 1 . 5 ± 0 . 4 9 6 8 . 5 ± 0 . 7 0 8 6 . 8 5 ± 0 . 7 8 8 7 . 1 ± 0 . 8 4 8 2 . 7 ± 0 . 4 9 8 1 . 5 ± 0 . 5 6 7 9 . 9 ± 0 . 7 1 8 3 . 7 ± 0 . 4 6 8 0 . 9 ± 0 . 7 8
atypical lymphocytes % 0 ± 0 0 ± 0 0 0 ± 0 0 0 ± 0 0 0 ± 0 0 ± 0 0 ± 0 0 ± 0 0 0 ± 0 0 ± 0
Monocytes % 1 . 4 ± 0 . 0 7 2 ± 0 . 7 1 1 . 2 ± 0 . 0 7 2 ± 0 0 1 . 2 ± 0 . 0 7 1 . 5 ± 0 . 7 1 1 . 4 ± 0 . 0 7 1 . 5 ± 0 . 7 1 1 . 2 ± 0 . 0 7 2 . 5 ± 0 . 7 1