Research Article

Topical Application Effect of the Isolectin Hydrogel (Cramoll 1,4) on Second-Degree Burns: Experimental Model

Table 2

Effect of topical administration of hydrogel containing 100 μg per mL isolectin Cramoll 1,4 on the biochemical parameters of Wistar rats. Doses performed in triplicate for each parameter. G1 = Treatment, G2 = Control. Mean ± SD ( 𝑛 = 2 ).

Parameters7th day14th day21st day28th day35th day
G1G2G1G2G1G2G1G2G1G2

Prothrombin time % 1 0 . 1 ± 0 . 0 7 9 . 7 ± 0 . 0 2 9 . 6 2 ± 0 . 1 1 1 0 . 1 ± 0 . 2 1 9 . 2 ± 0 . 2 1 1 0 . 1 ± 0 . 2 8 1 0 . 5 ± 0 . 7 1 1 0 . 1 ± 0 . 4 3 6 1 0 . 5 ± 0 . 7 0 9 . 7 ± 0 . 5 6
Fibrinogen mg/dL 4 6 0 . 5 ± 0 . 7 1 4 5 7 . 9 ± 0 . 0 7 4 0 7 . 1 ± 0 . 1 4 4 6 0 . 8 ± 0 . 2 1 4 1 2 ± 0 . 7 1 4 6 5 . 6 ± 0 . 4 7 3 8 0 ± 0 . 9 2 4 4 0 . 1 ± 0 . 1 4 2 4 0 7 . 7 ± 0 . 4 1 4 6 2 . 2 ± 0 . 3 4
Calcium mg/dL 1 0 . 3 ± 0 . 1 4 9 . 6 ± 0 . 4 6 8 . 4 ± 0 . 9 8 9 . 6 ± 0 . 4 2 1 1 . 6 ± 0 . 1 4 9 . 4 ± 0 . 1 6 1 1 . 5 ± 0 . 7 1 1 1 . 5 ± 0 . 6 5 8 9 . 7 ± 0 . 5 9 1 0 . 1 ± 0 . 4 2
Alkaline phosphatase U/L 1 9 3 . 6 ± 0 . 5 6 1 9 9 . 6 ± 0 . 4 9 2 1 2 . 7 ± 0 . 4 2 2 0 1 . 4 ± 0 . 5 7 2 0 8 ± 0 . 7 1 1 9 8 . 2 ± 0 . 3 1 2 7 5 ± 0 . 7 1 2 4 4 . 6 ± 0 . 6 0 1 2 0 9 . 7 ± 0 . 3 8 2 1 9 . 6 ± 0 . 6 2
Gamma glutamyl transferase U/L 5 ± 0 0 5 . 9 ± 0 . 1 4 5 . 7 ± 0 . 3 5 5 . 7 ± 0 . 2 9 5 . 8 ± 0 . 1 4 5 . 9 ± 0 . 0 2 5 . 3 ± 0 . 0 7 5 . 2 ± 0 . 0 1 2 5 . 6 ± 0 . 1 4 6 . 1 ± 0 . 7 2
Oxalic transaminase glutamic U/L 1 4 2 ± 0 . 0 7 1 7 6 . 6 ± 0 . 5 4 1 3 6 . 5 ± 0 . 7 1 2 0 8 . 2 ± 0 . 3 3 1 9 3 ± 0 . 7 1 1 7 9 . 9 ± 0 . 0 4 1 4 1 . 5 ± 0 . 6 4 1 5 6 . 6 ± 0 . 5 0 6 1 7 7 . 9 ± 0 . 1 5 1 7 8 . 8 ± 0 . 3 1
Transaminase glutamico piruvica U/L 6 0 . 7 ± 0 . 4 2 5 0 . 8 ± 0 . 1 9 5 5 . 7 ± 0 . 0 4 5 4 . 5 ± 0 . 5 8 4 7 ± 0 . 4 2 4 8 . 7 ± 0 . 3 3 4 8 . 5 ± 0 . 6 3 5 1 . 9 ± 0 . 1 2 9 5 8 . 5 ± 0 . 7 1 6 0 . 5 ± 0 . 7 8
Urea mg/dL 4 6 . 3 ± 0 . 4 9 4 6 . 9 ± 0 . 0 5 4 3 . 7 ± 0 . 3 5 5 0 . 6 ± 0 . 9 1 4 0 ± 0 . 7 1 4 5 . 9 ± 0 . 0 6 4 1 . 5 ± 0 . 7 1 4 6 . 8 ± 0 . 3 3 1 3 7 . 9 ± 0 . 1 1 4 1 . 5 ± 0 . 6 8
Creatinine mg/dL 0 . 2 ± 0 . 0 7 0 . 6 ± 0 . 0 4 0 . 5 ± 0 . 0 7 0 . 6 ± 0 . 1 2 0 . 4 ± 0 . 0 7 0 . 6 ± 0 . 0 1 0 . 6 ± 0 . 0 4 0 . 5 0 ± 0 . 0 1 1 0 . 5 ± 0 . 1 4 0 . 4 ± 0 . 0 4
Amylase U/L 8 3 8 ± 0 . 1 4 8 4 6 . 6 ± 0 . 5 6 7 8 9 ± 0 . 7 1 8 6 6 . 7 ± 0 . 4 2 8 0 8 . 3 ± 0 . 8 7 8 8 7 . 5 ± 0 . 7 1 8 5 6 . 6 ± 0 . 8 4 7 9 9 . 7 ± 0 . 4 6 9 8 1 4 . 5 ± 0 . 7 1 8 0 9 . 8 ± 0 . 2 7